Abstract: Recently, under the influence of the Mozhugongka earthquake swarm, two major structural buildings in the earthquake-stricken area have been damaged to varying degrees. Through field investigation, the seismic damage characteristics of stone-wood structure and frame structure houses in the affected areas were summarized and analyzed, and it was found that the main reasons for the serious damage of stone-wood structure houses were that the design of the houses was not conducive to earthquake resistance, poor construction quality, long construction age(built for a long time), and frequent earthquakes in a short period of time aggravated the seismic damage, while the main reasons for the damage of the frame-structured were the substandard construction quality and the continuous effect of seismic force. In this paper, the seismic damage phenomena and causes of the two structures are described in detail, and some follow-up suggestions are put forward.